Best Sikeston Hotels

Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown and within walking distance to many shops and restaurants. Settle in for a relaxing stay in one of our modern guest rooms. Enjoy the convenience of a mini-refrigerator, microwave, free WiFi, coffeemaker, 42-inch flat-screen TV with premium cable channels and work desk with ergonomic chair. Upgrade to a studio suite for extra space and a separate seating area. Start each day with our free hot breakfast or, if you’re in a hurry, grab one of Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stop by our Treats Shop any time of day or night for a quick snack or beverage. Stay in shape with a workout in our 24-hour fitness center or take a dip in our indoor heated pool. Plan a meeting in our 700 sq. ft. of meeting space fully equipped with A/V equipment.

Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotel’s address in Sikeston, MO surrounds you with fun and nearby attractions. Thanks to a convenient location close to I55,I60 and nearby companies, including, Monsanto, Cargill, and Siemens, John Deere, Orgill, Tyson, Unilever and Sikeston Power Plant. In addition, we provide guests with a selection of handy services at our state of the art Business Center. Sikeston is also home to the annual Sikeston Jaycee Bootheel Rodeo, which draws large crowds every August. Our accommodations are close to shops and dining venues. Whether you’re staying in Sikeston, MO for business or pleasure, we have the amenities to satisfy your needs. Connecting to colleagues and family is easy with the free high speed Internet access, and mornings are great with a cup of fresh coffee and gooey cinnamon roll from our complimentary, hot Express Start breakfast bar. Go for a dip in the indoor heated pool or burn calories in our state of the art Fitness Center. If you are looking for lodging in Sikeston, MO, our hotel is the smart choice.

Our brand-new hotel in Sikeston, MO is conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to a variety of shops and restaurants. Our rooms and suites include a work desk, personalized voice mail, and free high-speed internet access to keep you on task. Our free, fresh breakfast options include fluffy omelets, crispy bacon, mini waffles with toppings, sweet breads, Greek yogurt, and fresh fruit. For guests on the go, we offer grab-n-go breakfast options. A hearty variety of savory or sweet options to fuel your morning. An oversized fitness center features all the essential equipment you need. Flexible meeting space options to fit your needs and we are conveniently located near Orgill, Do it Best, and Unilever.

Find comfort at the newly-opened TownePlace Suites Sikeston. Our pet friendly hotel in Sikeston, MO​ is conveniently located off Highway 60 and Interstate 55, close to historic downtown and a variety of local shops and restaurants. Our fresh and clean, extended stay suites feature separate living and sleeping areas, plus fully-equipped kitchens. Well-lit work desks, personalized voice mail and free high-speed internet access will help keep you on task. Start your day with free breakfast daily! Enjoy fluffy omelets, crispy bacon, mini waffles with toppings, sweet breads, Greek yogurt and fresh fruit. In the evenings, visit Bohannon's, our on-site restaurant offering American cuisine in a casual setting. Stay fit from our modern fitness center and indoor swimming pool. Utilize on-site faxing, copying and printing services from our well-placed Sikeston hotel near Orgill, Do it Best and Unilever. Whether you're in town for business or leisure, have a successful stay at TownePlace Suites Sikeston.

Located in Sikeston, Comfort Inn & Suites Sikeston I-55 is a 1-minute drive from City of Miner Convention Center and 5 minutes from Sikeston Depot Museum. This hotel is 29.5 mi (47.4 km) from Ohio River Valley and 17.6 mi (28.4 km) from Mississippi River. Don't miss out on recreational opportunities including an indoor pool and a fitness center. Featured amenities include a business center, a 24-hour front desk, and laundry facilities. Free self parking is available onsite. Make yourself at home in one of the 64 air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected. Bathrooms with bathtubs or showers are provided. Conveniences include phones, as well as desks and coffee/tea makers.

Located in Sikeston, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is in a rural location, within a 5-minute drive of City of Miner Convention Center and Sikeston Depot Museum. This hotel is 29.5 mi (47.4 km) from Ohio River Valley and 17.6 mi (28.3 km) from Mississippi River. Make use of convenient amenities, which include complimentary wireless internet access and a vending machine. A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 6:00 AM to 9:00 AM. Featured amenities include a 24-hour front desk, coffee/tea in a common area, and a vending machine. Free self parking is available onsite. Make yourself at home in one of the 40 air-conditioned rooms featuring refrigerators. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have shower/tub combinations and complimentary toiletries. Conveniences include desks and blackout drapes/curtains, as well as phones with free local calls.

Welcome to Days Inn and Suites by Wyndham Sikeston offering easy access to major highways I-55 I-57 and US-62 as well as Cape Girardeau Regional Airport CGI. We are minutes from Sikeston Depot Museum City of Miner Convention Center and Sikeston Rodeo Grounds which hosts the annual Sikeston Jaycee Bootheel Rodeo. Grab a bite and have a laugh at Lamberts Cafe or shop for bargains at Sikeston Factory Outlet Stores - both within a mile of our doors. Our inviting all-suite hotel will help you feel at home with free light breakfast and WiFi plus a fitness center.