Hotels in Cape Girardeau

Best Cape Girardeau Hotels

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25 Best Hotels to Stay in Cape Girardeau

Find great hotels in Cape Girardeau on Trip.com! Read guest reviews, compare the latest prices, and explore hotel details to choose your perfect stay.
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Closest to Downtown
Highest Rated
Drury Inn & Suites Cape Girardeau Hotels in Cape Girardeau
Drury Inn & Suites Cape Girardeau Hotels in Cape GirardeauDrury Inn & Suites Cape Girardeau Hotels in Cape GirardeauDrury Inn & Suites Cape Girardeau Hotels in Cape GirardeauDrury Inn & Suites Cape Girardeau Hotels in Cape GirardeauDrury Inn & Suites Cape Girardeau Hotels in Cape GirardeauDrury Inn & Suites Cape Girardeau Hotels in Cape Girardeau
99+
Hotels in Cape Girardeau
Indoor swimming pool
Gym
Private parking
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System. Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall. Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include a business center, express check-out, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Great
100 reviews
9.2/10
1 night
From VND 2,482,181
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Fairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau
Fairfield Inn & Suites Cape Girardeau Hotels in Cape GirardeauFairfield Inn & Suites Cape Girardeau Hotels in Cape GirardeauFairfield Inn & Suites Cape Girardeau Hotels in Cape GirardeauFairfield Inn & Suites Cape Girardeau Hotels in Cape GirardeauFairfield Inn & Suites Cape Girardeau Hotels in Cape GirardeauFairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau
63
Hotels in Cape Girardeau
Gym
24-hour front desk
Smoking area
"Jenn was the evening clerk and was efficient and very pleasant."
Great
51 reviews
9.2/10
1 night
From VND 2,508,153
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Courtyard Cape Girardeau Downtown Hotels in Cape Girardeau
Courtyard Cape Girardeau Downtown Hotels in Cape GirardeauCourtyard Cape Girardeau Downtown Hotels in Cape GirardeauCourtyard Cape Girardeau Downtown Hotels in Cape GirardeauCourtyard Cape Girardeau Downtown Hotels in Cape GirardeauCourtyard Cape Girardeau Downtown Hotels in Cape GirardeauCourtyard Cape Girardeau Downtown Hotels in Cape Girardeau
56
Hotels in Cape Girardeau
Gym
Public parking
24-hour front desk
"Very lovely hotel just not much to do with the corona virus going around :/"
Amazing
94 reviews
9.4/10
1 night
From VND 3,406,043
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Serenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape Girardeau
Serenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape GirardeauSerenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape GirardeauSerenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape GirardeauSerenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape GirardeauSerenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape GirardeauSerenity South -- Gardens, River-Views, and Refreshing Space Hotels in Cape Girardeau
31
Hotels in Cape Girardeau
Golf course
Horse riding
Hiking
Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.Excellent fenced back yard..About customRules:Back yard is shared with the other side of the duplex. Please respect their use of the common space..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:Events allowed: family gatherings, birthday parties, weddings.Maximum event attendees: 50,Parties or events must okayed before arrival..
Outstanding
62 reviews
10.0/10
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Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape Girardeau
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape GirardeauArtistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape GirardeauArtistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape GirardeauArtistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape GirardeauArtistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape GirardeauArtistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Hotels in Cape Girardeau
34
Hotels in Cape Girardeau
Wi-Fi in public areas
Enjoy the Luxury of being near Downtown with a short Bike Ride or Walk from our Adventurous 2 Bedroom Suite. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Then, when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.The Space is perfect for Longer Stays for Traveling Nurses or Workers, Relocation for families before a move and also Staycations! Can sleep 4 in beds and one person on a couch if needed (though couch is small)Here are Some of our Guests Favorite Things:• Fully Stocked Kitchen• Indoor Swing/Reading Area• Fast WIFI• Themed & Comfy 10" Memory Foam Beds in Bedrooms• Bicycles & Air pump• Large Bathtub• Board Games• Large Dining Table that can be used as a Work Space• Overall unique spaceAbout pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.Our space is not suited for very small children..About customRules:Quiet time after 10. The home is an older home and sound carries. We have long-term tenants below..No access to blacktop roof outside.,PLEASE DO NOT SIGN OUT OF OUR NETFLIX. PLEASE Limit Towel Use during your stay..About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 21.About events:No events allowed.
Amazing
20 reviews
9.6/10
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Charming 3-bedroom house near downtown Hotels in Cape Girardeau
Charming 3-bedroom house near downtown Hotels in Cape GirardeauCharming 3-bedroom house near downtown Hotels in Cape GirardeauCharming 3-bedroom house near downtown Hotels in Cape GirardeauCharming 3-bedroom house near downtown Hotels in Cape GirardeauCharming 3-bedroom house near downtown Hotels in Cape GirardeauCharming 3-bedroom house near downtown Hotels in Cape Girardeau
31
Hotels in Cape Girardeau
Located in Cape Girardeau, enjoy what this 3-bedroom house has to offer. With a nice king bed, a charming full bed, and a fabulous twin bed, guests will feel right at home. The property features heating, WiFi, a washing machine, and AC for convenience. There are 2 bathrooms with showers available. Experience the magic of Cape Girardeau at our house. Fenced-in yard outside for pets or children to play and plenty of space inside for the family! About pets:Pets allowed: dogs less than 50 lbs per pet (limit one pet total).About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About customRules:-Take out any trash -Place dirty towels, sheets, and comforters into separate piles in basement landing.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
Outstanding
1 review
10.0/10
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Holiday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau
Holiday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape GirardeauHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape GirardeauHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape GirardeauHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape GirardeauHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape GirardeauHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau
99
Hotels in Cape Girardeau
Public parking
Gym
24-hour front desk
"The hotel was very clean and comfortable. Our suite was generously sized and comfortably slept all 5 of us. There was nice amenities from a heated indoor pool to a nice, hot breakfast, to a fitness room and conference room."
Great
99 reviews
9.2/10
1 night
From VND 2,515,574
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Hampton Inn Cape Girardeau I-55 East Hotels in Cape Girardeau
Hampton Inn Cape Girardeau I-55 East Hotels in Cape GirardeauHampton Inn Cape Girardeau I-55 East Hotels in Cape GirardeauHampton Inn Cape Girardeau I-55 East Hotels in Cape GirardeauHampton Inn Cape Girardeau I-55 East Hotels in Cape GirardeauHampton Inn Cape Girardeau I-55 East Hotels in Cape GirardeauHampton Inn Cape Girardeau I-55 East Hotels in Cape Girardeau
99+
Hotels in Cape Girardeau
Public parking
Gym
24-hour front desk
incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you’re pressed for time, grab Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed® watching the 37-inch HDTV or with your laptop on the provided lap desk.
Amazing
98 reviews
9.6/10
1 night
From VND 3,012,752
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Drury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape GirardeauDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape GirardeauDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape GirardeauDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape GirardeauDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape GirardeauDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau
99+
Hotels in Cape Girardeau
Indoor swimming pool
Gym
Private parking
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System. Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall. Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include a 24-hour business center, a 24-hour front desk, and laundry facilities. Event facilities at this hotel consist of a conference center and meeting rooms. Free self parking is available onsite. Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Amazing
100 reviews
9.4/10
1 night
From VND 2,693,668
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Rockwood Inn Hotels in Cape Girardeau
Rockwood Inn Hotels in Cape GirardeauRockwood Inn Hotels in Cape GirardeauRockwood Inn Hotels in Cape GirardeauRockwood Inn Hotels in Cape GirardeauRockwood Inn Hotels in Cape GirardeauRockwood Inn Hotels in Cape Girardeau
99+
Hotels in Cape Girardeau
Parking
Wi-Fi in public areas
Conference room
With a stay at Rockwood Inn in Cape Girardeau, you'll be within a 5-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.2 mi (0.4 km) from Southeast Missouri State University and 0.7 mi (1.2 km) from Show Me Center. Take in the views from a garden and make use of amenities such as complimentary wireless internet access and a picnic area. Free self parking is available onsite. Make yourself at home in one of the 7 air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected.
Amazing
10 reviews
9.6/10
1 night
From VND 3,684,314
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Latest reviews for Cape Girardeau hotels

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Browse these genuine traveler ratings and real guest reviews to find the best Cape Girardeau hotels.
8.6/10
Very Good
BBevMayThe lady behind the desk was friendly. The lady in the breakfast area was always cleaning and making sure it was clean. Clean room. We only stayed one night so it was perfect.
Pear Tree Inn Cape Girardeau Medical Center Hotels in Cape Girardeau

Pear Tree Inn Cape Girardeau Medical Center

Hotel near Cape Girardeau
Price per night from:VND 1,847,722
8.0/10
Very Good
GGuest UserLoved it! So clean & everyone was so kind. I’ll definitely visit again.
Candlewood Suites Cape Girardeau Hotels in Cape Girardeau

Candlewood Suites Cape Girardeau

Hotel near Cape Girardeau
Price per night from:VND 1,836,592
6.7/10
GGuest UserCheck in was fine… the man explained everything after my husband asked why all travelers in the room had to present IDs (including our two teenage sons). The room was pretty clean except there was blood on the comforter. All the employees were friendly. Overall, a decent stay once the linens were taken care of.
Quality Inn Hotels in Cape Girardeau

Quality Inn

Hotel near Cape Girardeau
Price per night from:VND 1,521,217
5.4/10
GGuest Userthis is a nice hotel. there is a restaurant next to it.
Town House Inn Cape Girardeau Hotels in Cape Girardeau

Town House Inn Cape Girardeau

Hotel near Cape Girardeau
Price per night from:VND 1,847,722

FAQs About Cape Girardeau Hotels

Where can I find the best hotels in Cape Girardeau?

Cape Girardeau has some of the best hotels for you to select. Whether you're traveling for business or on a vacation, Courtyard Cape Girardeau Downtown (from VND 3,179,715), Fairfield Inn & Suites Cape Girardeau (from VND 2,552,676) and Candlewood Suites Cape Girardeau (from VND 1,977,582) are preferred hotels.

Where can you find hotels with excellent breakfast in Cape Girardeau?

What are some hotels with pools in Cape Girardeau?

Where can I find the best hotel discounts in Cape Girardeau?

Trip.com provides various promotions and discounts for users all year round. You can check the promotions page to see what promotions are available on Trip.com.

Which hotels are recommended near Southeast Missouri State University in Cape Girardeau?

For Cape Girardeau hotels near Southeast Missouri State University, many travelers recommend Courtyard Cape Girardeau Downtown (from VND 3,179,715), The Riverview (from VND 2,775,293) and Rockwood Inn (from VND 4,021,950) for their great location and service.

Cape Girardeau Hotels Info

Number of Reviews
1,195
Total Properties
25
Average Price (Weekdays)
VND 3,735,256
Average Price (Weekends)
VND 4,375,429