With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Featured amenities include a business center, express check-out, and a 24-hour front desk. Free self parking is available onsite.
Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Featured amenities include a 24-hour business center, a 24-hour front desk, and laundry facilities. Event facilities at this hotel consist of a conference center and meeting rooms. Free self parking is available onsite.
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest. This casino hotel is 0.1 mi (0.2 km) from Riverfront Park and 0.1 mi (0.2 km) from Isle Casino Cape Girardeau.
Enjoy the recreation opportunities such as a casino or make use of other amenities including complimentary wireless internet access.
Enjoy American cuisine at Beacon 53, one of the hotel's many dining establishments, which include 2 restaurants and a coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. Cooked-to-order breakfasts are available daily from 7:00 AM to 10:00 AM for a fee.
Featured amenities include a 24-hour front desk and an elevator. Free self parking is available onsite.
Make yourself at home in one of the 69 air-conditioned rooms featuring LED televisions. Your pillowtop bed comes with premium bedding. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have showers and hair dryers.
With a stay at Rockwood Inn in Cape Girardeau, you'll be within a 5-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.2 mi (0.4 km) from Southeast Missouri State University and 0.7 mi (1.2 km) from Show Me Center.
Take in the views from a garden and make use of amenities such as complimentary wireless internet access and a picnic area.
Free self parking is available onsite.
Make yourself at home in one of the 7 air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected.
The lady behind the desk was friendly. The lady in the breakfast area was always cleaning and making sure it was clean. Clean room. We only stayed one night so it was perfect.
incredible service at our Cape Girardeau, MO hotel.
From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread.
This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you’re pressed for time, grab Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities.
End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed® watching the 37-inch HDTV or with your laptop on the provided lap desk.
Outstanding
95 reviews
4.8/5
Price from
PHP 6,925
per night
Check Availability
See All Hotels in Cape Girardeau
What Travelers Said About the Best Hotels in Cape Girardeau
See all
Browse these genuine traveler ratings and real guest reviews to find the best Cape Girardeau hotels.
4.6/5
Outstanding
GGuest UserThe hotel was very clean and comfortable. Our suite was generously sized and comfortably slept all 5 of us. There was nice amenities from a heated indoor pool to a nice, hot breakfast, to a fitness room and conference room.
BBevMayThe lady behind the desk was friendly. The lady in the breakfast area was always cleaning and making sure it was clean. Clean room. We only stayed one night so it was perfect.
GGuest UserCheck in was fine… the man explained everything after my husband asked why all travelers in the room had to present IDs (including our two teenage sons). The room was pretty clean except there was blood on the comforter. All the employees were friendly. Overall, a decent stay once the linens were taken care of.
Trip.com provides various promotions and discounts for users all year round. You can check the promotions page to see what promotions are available on Trip.com.