Find 4-Star Hotels in Rochester

The Hilton Rochester Mayo Clinic Area is conveniently located in the heart of downtown Rochester, just two short blocks from the world-famous Mayo Clinic. The hotel is 8 miles from Rochester International Airport, with service to Chicago O’Hare and Atlanta. Interstate 90, the main thoroughfare from Madison, Wisconsin: Chicago, Illinois: and points east is also 8 miles from downtown. I-35 North is 40 minutes away, providing access from Des Moines, Iowa: St. Louis, Missouri: and Kansas City. The Minneapolis St Paul International Airport is 80 miles away, and there are up to 50 shuttles a day which fly between the city and that airport. We are renowned for personalized friendly guest service. Our tastefully decorated hotel features contemporary elegance, designed to ensure every need of the medical patient, corporate, conference and any other traveler. Spacious guest rooms of various sizes and a variety of suites offer a long list of guest amenities with generous work surfaces, comfortable seating, luxurious Hilton bedding, and free high-speed internet access in addition to other services. WiFi is available in public areas throughout the hotel. A comfortable and spacious Tech Lounge is located in the Main Lobby for guest use. Our guests enjoy the following services and amenities: -A chauffeur-driven limousine with on-demand transfer to and from Mayo Clinic facilities and various locations within the city. -A Steak House Signature Restaurant, open for Lunch and Dinner -A casual Restaurant open for Breakfast, Lunch and Dinner -A Herb ‘n Kitchen outlet -Room Service -Concierge Services -Valet Parking -Indoor Swimming Pool, Whirlpool, Saunas and Sundeck. -A Spacious Precor Exercise Facility. -An attractive outdoor Terrace designed for relaxation and exercise on the roof of the fourth floor of the hotel. The Hilton Rochester Mayo Clinic Area Conference Center has 24,000 square feet of flexible meeting and banquet room including two magnificent ballrooms with 19-foot ceilings, three breakout rooms, and ample pre-function space. The Conference Center has state-of-the-art audio visual equipment. Our friendly catering services staff attends to every detail for the most successful event. Whether it is for a conference, banquet, seminar, wedding or reception, our facilities with panoramic views over the city provide the perfect location. This downtown Hilton hotel, just one block from the Mayo Civic Center, is connected to the city skyway system, providing a climate-controlled environment for guests to access the Mayo Clinic, University Square Shopping Mall, downtown restaurants, Mayo Civic Center, University of Minnesota Rochester campus, the Courthouse and many other locations. The Mayo Clinic Art Tour, Mayowood, home of Dr. Charles Mayo: Rochester Art Center, and Rochester Civic Theater are among the various locations of interest within the city. Amish Country, the Mississippi Valley and Lanesboro, a quaint Arts village, are all within a 40-minute drive of the hotel. The Mall of America is 80 miles away and adjacent to the Minneapolis St. Paul Airport. Transportation is available. Hilton Rochester Mayo Clinic Area is the perfect location to stay and enjoy a relaxing respite in contemporary elegance, with first-class personalized, friendly service.

Wellness Hotel near The Mayo Clinic Hospital​Our recently-inaugurated hotel is conveniently located across the street from the Mayo Clinic Hospital, St. Marys Campus and close to the Methodist Hospital Campus, making it the ideal place to stay if you're in town for medical appointments or visiting loved ones at the hospital.EVEN Hotel Rochester - St. Marys Area is also close to downtown Rochester for great shopping and dining options. Art enthusiasts can go to the Rochester Art Center, while history buffs can explore The Mayowood Mansion. Plus, we are just minutes from the Rochester International Airport, Quarry Hill Nature Center, the University of Minnesota Rochester and the Galleria at University Square.​​Our Rochester hotel also offers a new perspective on wellness with a best-in-class athletic studio, and customizable healthy entrees at our restaurant EVEN Kitchen & Bar, helping you stay fit while traveling.​

A stay at The Towers At Kahler Grand Hotel places you in the heart of Rochester, just a 4-minute walk from Mayo Clinic and within a 5-minute drive of Mayo Clinic Hospital - Saint Marys Campus. This hotel is 0.1 mi (0.2 km) from Shops University Square and 0.2 mi (0.4 km) from University of Minnesota-Rochester. Take advantage of recreation opportunities including an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and gift shops/newsstands. Enjoy American cuisine at Lord Essex Tavern & Grill, one of the hotel's 2 restaurants, or stay in and take advantage of the room service (during limited hours). Snacks are also available at the coffee shop/cafe. Mingle with other guests at the complimentary reception, held daily. Quench your thirst with your favorite drink at the bar/lounge. A complimentary self-serve breakfast is served daily from 6:00 AM to 9:00 AM. Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk. Free valet parking is available onsite. Stay in one of 44 guestrooms featuring plasma televisions. Your bed comes with down comforters and premium bedding. Complimentary wireless internet access keeps you connected, and digital programming is available for your entertainment. Bathrooms feature showers, designer toiletries, and hair dryers.

Welcome to our Mynt House, our serene haven 7 mins away from Mayo Clinic, just a short walk from the tranquil Silver Lake and shopping. This mid-century fully furnished modern gem is designed for your ultimate comfort. Enjoy the office space, TV entertainment, blasting fast Internet, washer/dryer & fully equipped kitchen for cooking. We offer one king size bed, one queen bed, 2 full size beds and one twin-size bed. Thoughtfully updated to provide a space that feels like home during your stay. Spacious. Stylish. Super comfortable.Enjoy 4 thoughtfully designed bedrooms, including a king bed, queen bed, two full beds, and a twin, perfect for families, caregivers, or business travelers needing space and rest. With a dedicated office space, ultra-fast Wi-Fi, smart TVs with streaming, and a fully equipped kitchen, you’ll have everything you need for short or extended stays.Top Features:- Prime location: 7 mins to Mayo Clinic / Saint Marys Hospital- 4 bedrooms / 5 beds for ultimate flexibility - 1 full bathroom with bidet (a must-have for many guests!) - Washer & dryer in unit- Keurig coffee station - High-speed internet + Netflix, Disney+, Chromecast- Fresh linens, towels, bathroom essentials- Self check-in & digital home guide- Free private parking- No shared spaces – entire home is yoursBedroom Layout:- Bedroom 1: Queen bed - Bedroom 2: Two Full beds - Bedroom 3: King bed - Bedroom 4: Twin bed Guest Experience:From the moment you book, you’ll receive a warm welcome via text and email, along with a link to our digital home guide, your go-to for Wi-Fi info, check-in instructions, house rules, and our favorite local spots for food, coffee, and shopping. We’re always just a message away to assist you throughout your stay.Why Guests Love Us:- Impeccable cleanliness and comfort - Quiet, safe neighborhood - Easy access to Mayo, dining, and scenic trails - Superhost-level care and attentionWhether you're in town for a short visit or an extended medical stay, Mynte House offers peace, convenience, and modern comfort—just minutes from the heart of Rochester.Book your stay today—homes like this near Mayo book FAST!About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.