Hotels in Cape Girardeau County

Best Cape Girardeau County Hotels

Enter your dates for prices and availability of the best hotels in Cape Girardeau County.

Swipe up to view more
Filter by:
Hotel Star Rating
≤2345
Guest Rating
Amazing 9+Great 8+Good 7+Pleasant 6+
Property Type
HotelApartmentVacation homeChaletMotel
Property facilities & services
Wi-Fi in public areas24-hour front deskParking availableFree parkingGymPoolElevatorWake-up callPets welcomeBarbecueGolf courseConference roomSmoking areaLuggage storageRestaurantWater parkBarEV charging station

35 Best Hotels to Stay in Cape Girardeau County

Find great hotels in Cape Girardeau County on Trip.com! Read guest reviews, compare the latest prices, and explore hotel details to choose your perfect stay.
Most Booked
Lowest Price
Closest to Downtown
Highest Rated
Drury Inn & Suites Cape Girardeau Hotels in Cape Girardeau County
Drury Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyDrury Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyDrury Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyDrury Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyDrury Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyDrury Inn & Suites Cape Girardeau Hotels in Cape Girardeau County
99+
Hotels in Cape Girardeau County
Indoor swimming pool
Gym
Private parking
+6
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System. Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall. Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include a business center, express check-out, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Great
100 reviews
9.2/10
1 night
From PHP 5,280
Check Availability
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau County
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau CountyLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau CountyLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau CountyLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau CountyLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau CountyLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Hotels in Cape Girardeau County
64
Hotels in Cape Girardeau County
Parking
EV charging station
Gym
+5
"Still good to live in"
Very Good
97 reviews
8.6/10
1 night
From PHP 4,932
Check Availability
Fairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau County
Fairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyFairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyFairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyFairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyFairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau CountyFairfield Inn & Suites Cape Girardeau Hotels in Cape Girardeau County
63
Hotels in Cape Girardeau County
Gym
24-hour front desk
Smoking area
+2
"Jenn was the evening clerk and was efficient and very pleasant."
Great
52 reviews
9.2/10
1 night
From PHP 5,785
Check Availability
Relax in the country at Countryside Villas! - Villa A Hotels in Cape Girardeau County
Relax in the country at Countryside Villas! - Villa A Hotels in Cape Girardeau CountyRelax in the country at Countryside Villas! - Villa A Hotels in Cape Girardeau CountyRelax in the country at Countryside Villas! - Villa A Hotels in Cape Girardeau CountyRelax in the country at Countryside Villas! - Villa A Hotels in Cape Girardeau CountyRelax in the country at Countryside Villas! - Villa A Hotels in Cape Girardeau County
8
Hotels in Cape Girardeau County
Wi-Fi in public areas
Countryside Villa #A has recently been remodeled and updated and includes 2 bedrooms and 2 baths as well as a nice large equipped kitchen and living area and a washer and dryer is available in the utility room if needed. Its located on a quiet, relaxing countryside setting just 2 miles from I-55 in the Fruitland area yet only a few minutes from Jackson and Cape Girardeau. Other area attractions include the Flickerwood Arena, Trail of Tears State Park, Osage Center and Show Me Center as well as several restaurants and places to shop. Whether you're here for an event in the event center located on the premises or an event in the area or just to relax, you'll love the peace and quiet of the country surroundings at Countryside Villas.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.Owner is not responsible of unsupervised children.About customRules:Unauthorized events are strictly prohibited if found a violation to house rules the booking will be cancel with no refund and guests need to vacate..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 21.About events:No events allowed.
Outstanding
10.0/10
Check Availability
Villa B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau County
Villa B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau CountyVilla B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau CountyVilla B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau CountyVilla B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau CountyVilla B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau CountyVilla B offers peace and quiet with beautiful views of the countryside. Hotels in Cape Girardeau County
11
Hotels in Cape Girardeau County
Wi-Fi in public areas
Newly updated and remodeled with space to unwind and relax. Villa B offers a patio to enjoy the countryside view, listen to the birds and watch horses in a distant pasture. Its located only minutes from Jackson and Cape Girardeau in the Fruitland area with easy access off I-55. Convenience stores and restaurants are conveniently located within 2 miles. It has 2 bedrooms and 2 baths which can be used privately if desired, a laundry room with washer and dryer, living room and a fully furnished kitchen.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 21.About events:No events allowed.
Outstanding
10.0/10
Check Availability
Charming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau County
Charming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau CountyCharming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau CountyCharming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau CountyCharming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau CountyCharming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau CountyCharming 2-bedroom house in delightful Jackson with AC, WiFi Hotels in Cape Girardeau County
12
Hotels in Cape Girardeau County
Wi-Fi in public areas
Come unwind and enjoy your home away from home in Jackson with 2 bedrooms. This charming house features a king bed and a queen bed, perfect for a wonderful and tranquil stay. Enjoy the convenience of heating, WiFi, AC, a washing machine, and an iron. Plus, enjoy the beautiful country views on the back patio.About pets:No pets allowed.About children:Children allowed: ages 0-17.About smoking:Smoking is not permitted.About events:No events allowed.
Outstanding
5 reviews
10.0/10
Check Availability
Holiday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau County
Holiday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau CountyHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau CountyHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau CountyHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau CountyHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau CountyHoliday Inn Express & Suites Cape Girardeau I-55 Hotels in Cape Girardeau County
99
Hotels in Cape Girardeau County
Public parking
Gym
24-hour front desk
+10
"The hotel was very clean and comfortable. Our suite was generously sized and comfortably slept all 5 of us. There was nice amenities from a heated indoor pool to a nice, hot breakfast, to a fitness room and conference room."
Great
100 reviews
9.2/10
1 night
From PHP 5,586
Check Availability
Drury Inn & Suites Jackson MO Hotels in Cape Girardeau County
Drury Inn & Suites Jackson MO Hotels in Cape Girardeau CountyDrury Inn & Suites Jackson MO Hotels in Cape Girardeau CountyDrury Inn & Suites Jackson MO Hotels in Cape Girardeau CountyDrury Inn & Suites Jackson MO Hotels in Cape Girardeau CountyDrury Inn & Suites Jackson MO Hotels in Cape Girardeau CountyDrury Inn & Suites Jackson MO Hotels in Cape Girardeau County
99+
Hotels in Cape Girardeau County
Outdoor swimming pool
Gym
Private parking
+7
With a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Lazy L Safari Park and Cape Girardeau Conservation Nature Center. This hotel is 10.2 mi (16.5 km) from Mississippi River and 10.4 mi (16.7 km) from Shawnee National Forest. Take advantage of recreational opportunities offered, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall. Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include a business center, express check-out, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 80 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Amazing
100 reviews
9.4/10
1 night
From PHP 5,363
Check Availability
Drury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau County
Drury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau CountyDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau CountyDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau CountyDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau CountyDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau CountyDrury Plaza Hotel Cape Girardeau Conference Center Hotels in Cape Girardeau County
99+
Hotels in Cape Girardeau County
Indoor swimming pool
Gym
Private parking
+7
The Drury Plaza Hotel Cape Girardeau Conference Center provides a great place for travelers to relax after a busy day. The Drury Plaza Hotel Cape Girardeau Conference Center offers a pleasant stay in Cape Girardeau for those traveling for business or leisure. The hotel is just 10km away from Cape Girardeau Regional Airport. Seeing Cape Girardeau's sights from this hotel is easy with West Park Lanes, The Apostolic Promise Church and Discover Life Church - Cape Girardeau all close by. At the end of a busy day, travelers can unwind and relax in the hotel or go out and enjoy the city. This Cape Girardeau hotel provides parking on site. According to our trusted guests, the facilities at this hotel are first-rate.
Amazing
100 reviews
9.4/10
1 night
From PHP 5,280
Check Availability
Tru by Hilton Cape Girardeau Hotels in Cape Girardeau County
Tru by Hilton Cape Girardeau Hotels in Cape Girardeau CountyTru by Hilton Cape Girardeau Hotels in Cape Girardeau CountyTru by Hilton Cape Girardeau Hotels in Cape Girardeau CountyTru by Hilton Cape Girardeau Hotels in Cape Girardeau CountyTru by Hilton Cape Girardeau Hotels in Cape Girardeau CountyTru by Hilton Cape Girardeau Hotels in Cape Girardeau County
51
Hotels in Cape Girardeau County
Parking
Gym
24-hour front desk
+2
From our daily free hot breakfast to our nightly cookie hour, Tru Cape Girardeau makes you feel at home. Located just off Interstate 55 at exit 99, we are conveniently located near the Cape Girardeau Sportsplex, Southeast Missouri State University, and the Conservation Nature Center. This beautiful hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. Stay connected to the office with free WiFi in every room or work from one of our quant business nooks located in the lobby. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns.
Amazing
9.4/10
1 night
From PHP 6,150
Check Availability
See All Hotels in Cape Girardeau County

Browse by hotel type

Immerse yourself in the vibrant atmosphere of Cape Girardeau County with our handpicked accommodation options

Most-booked Cape Girardeau County hotels

See all
Check out these top-booked hotels from the past 30 days!
No.1
Courtyard Cape Girardeau Downtown Hotels in Cape Girardeau
9.4/10
94 review

Courtyard Cape Girardeau Downtown

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.2
Candlewood Suites Cape Girardeau Hotels in Cape Girardeau
8.0/10
97 review

Candlewood Suites Cape Girardeau

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.3
The Riverview Hotels in Cape Girardeau
9.2/10
81 review

The Riverview

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.4
Pear Tree Inn Cape Girardeau West Hotels in Cape Girardeau
9.0/10
93 review

Pear Tree Inn Cape Girardeau West

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.5
Pear Tree Inn Cape Girardeau Medical Center Hotels in Cape Girardeau
8.6/10
96 review

Pear Tree Inn Cape Girardeau Medical Center

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.6
Quality Inn Hotels in Cape Girardeau
6.7/10
95 review

Quality Inn

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.7
Hampton Inn Cape Girardeau I-55 East Hotels in Cape Girardeau
9.6/10
99 review

Hampton Inn Cape Girardeau I-55 East

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.8
Jackson Town House Inn Hotels in Jackson
7.6/10
98 review

Jackson Town House Inn

Hotel near Jackson
"Good Location"
Select dates to view prices
No.9
Town House Inn Cape Girardeau Hotels in Cape Girardeau
5.4/10
37 review

Town House Inn Cape Girardeau

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices
No.10
Rockwood Inn Hotels in Cape Girardeau
9.6/10
11 review

Rockwood Inn

Hotel near Cape Girardeau
"Good Location"
Select dates to view prices

FAQs About Cape Girardeau County Hotels

Where can I find the best hotels in Cape Girardeau County?

Cape Girardeau County has some of the best hotels for you to select. Whether you're traveling for business or on a vacation, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau (from PHP 4,542), Courtyard Cape Girardeau Downtown (from PHP 7,070) and Candlewood Suites Cape Girardeau (from PHP 4,210) are preferred hotels.

What are some hotels with pools in Cape Girardeau County?

Where can you find hotels with excellent breakfast in Cape Girardeau County?

Where can I find the best hotel discounts in Cape Girardeau County?

Trip.com provides various promotions and discounts for users all year round. You can check the promotions page to see what promotions are available on Trip.com.

Cape Girardeau County Hotels Info

Highest Price
PHP 6,954
Number of Reviews
1,666
Total Properties
35
Weekday Avg. Price
PHP 7,726
Weekend Avg. Price
PHP 9,246