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Flights from Sioux Falls to Des Moines
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Cheap flight deals from Sioux Falls to Des Moines Starting at US$252

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip
      • FSD05:05 am
        6h 26m
        1 stop
        DSM11:31 am
        Thu, Feb 20|Sioux Falls - Des Moines|Delta Air Lines
        US$252US$616
        59% OFF
        59% OFF
        US$616US$252

        Choose Delta Air Lines flights from Sioux Falls to Des Moines. The one-way connecting flight with Delta Air Lines departs from Sioux Falls Regional Airport on Thu, Feb 20, arriving at Des Moines International Airport. One-way Prices start from US$252 including taxes and charges.

      • FSD05:02 pm
        24h 44m
        1 stop
        DSM05:46 pm
        Sat, Mar 15|Sioux Falls - Des Moines|American Airlines
        US$252US$616
        59% OFF
        59% OFF
        US$616US$252

        Choose American Airlines flights from Sioux Falls to Des Moines. The one-way connecting flight with American Airlines departs from Sioux Falls Regional Airport on Sat, Mar 15, arriving at Des Moines International Airport. One-way Prices start from US$252 including taxes and charges.

      • FSD12:40 pm
        3h 47m
        1 stop
        DSM04:27 pm
        Mon, Mar 31|Sioux Falls - Des Moines|Delta Air Lines
        US$261US$616
        57% OFF
        57% OFF
        US$616US$261

        Choose Delta Air Lines flights from Sioux Falls to Des Moines. The one-way connecting flight with Delta Air Lines departs from Sioux Falls Regional Airport on Mon, Mar 31, arriving at Des Moines International Airport. One-way Prices start from US$261 including taxes and charges.

      • FSD12:30 pm
        3h 9m
        1 stop
        DSM03:39 pm
        Sat, Mar 15|Sioux Falls - Des Moines|Delta Air Lines
        US$262
        US$262

        Choose Delta Air Lines flights from Sioux Falls to Des Moines. The one-way connecting flight with Delta Air Lines departs from Sioux Falls Regional Airport on Sat, Mar 15, arriving at Des Moines International Airport. One-way Prices start from US$262 including taxes and charges.

      • FSD11:00 am
        5h 30m
        1 stop
        DSM04:30 pm
        Sun, Feb 23|Sioux Falls - Des Moines|Delta Air Lines
        US$264
        US$264

        Choose Delta Air Lines flights from Sioux Falls to Des Moines. The one-way connecting flight with Delta Air Lines departs from Sioux Falls Regional Airport on Sun, Feb 23, arriving at Des Moines International Airport. One-way Prices start from US$264 including taxes and charges.

      • FSD09:15 am
        11h 24m
        1 stop
        DSM08:39 pm
        Thu, Feb 20|Sioux Falls - Des Moines|United Airlines
        US$356
        US$356

        Choose United Airlines flights from Sioux Falls to Des Moines. The one-way connecting flight with United Airlines departs from Sioux Falls Regional Airport on Thu, Feb 20, arriving at Des Moines International Airport. One-way Prices start from US$356 including taxes and charges.

      • FSD03:13 pm
        23h 19m
        1 stop
        DSM02:32 pm
        Sat, Mar 15|Sioux Falls - Des Moines|United Airlines
        US$358
        US$358

        Choose United Airlines flights from Sioux Falls to Des Moines. The one-way connecting flight with United Airlines departs from Sioux Falls Regional Airport on Sat, Mar 15, arriving at Des Moines International Airport. One-way Prices start from US$358 including taxes and charges.

      • FSD06:00 am
        14h 39m
        1 stop
        DSM08:39 pm
        Mon, Mar 31|Sioux Falls - Des Moines|United Airlines
        US$362
        US$362

        Choose United Airlines flights from Sioux Falls to Des Moines. The one-way connecting flight with United Airlines departs from Sioux Falls Regional Airport on Mon, Mar 31, arriving at Des Moines International Airport. One-way Prices start from US$362 including taxes and charges.

      • FSD09:15 am
        14h 15m
        1 stop
        DSM11:30 pm
        Sun, Feb 23|Sioux Falls - Des Moines|United Airlines
        US$401
        US$401

        Choose United Airlines flights from Sioux Falls to Des Moines. The one-way connecting flight with United Airlines departs from Sioux Falls Regional Airport on Sun, Feb 23, arriving at Des Moines International Airport. One-way Prices start from US$401 including taxes and charges.

      • FSD12:23 pm
        10h 7m
        1 stop
        DSM10:30 pm
        Thu, Feb 20|Sioux Falls - Des Moines|American Airlines
        US$468
        US$468

        Choose American Airlines flights from Sioux Falls to Des Moines. The one-way connecting flight with American Airlines departs from Sioux Falls Regional Airport on Thu, Feb 20, arriving at Des Moines International Airport. One-way Prices start from US$468 including taxes and charges.

      • FSD01:00 pm
        3h 5m
        Nonstop
        DSM02:00 pm
        Wed, Feb 26|Sioux Falls - Des Moines|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Sioux Falls to Des Moines Flight Time

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL5234

    Delta Air Lines

    01:20 pm

    FSD

    1.1h

    02:28 pm

    MSP

    SMTWTFS
    Search

  2. DL1476

    Delta Air Lines

    03:50 pm

    MSP

    1.8h

    06:35 pm

    DTW

    SMTWTFS

  3. DL5087

    Delta Air Lines

    07:55 pm

    DTW

    1.8h

    08:45 pm

    DSM

    SMTWT-S

  4. DL5234

    Delta Air Lines

    01:20 pm

    FSD

    1.1h

    02:28 pm

    MSP

    SMTWTFS
    Search

  5. DL5063

    Delta Air Lines

    03:30 pm

    MSP

    1.2h

    04:40 pm

    DSM

    SMTWT-S

  6. DL5238

    Delta Air Lines

    04:09 pm

    FSD

    1.1h

    05:15 pm

    MSP

    SMTWTFS
    Search

  7. DL5253

    Delta Air Lines

    08:05 pm

    MSP

    1.2h

    09:16 pm

    DSM

    SMTWTFS

  8. DL1006

    Delta Air Lines

    05:00 am

    FSD

    1.1h

    06:07 am

    MSP

    SMTWTFS
    Search

  9. DL4998

    Delta Air Lines

    09:00 am

    MSP

    1.2h

    10:11 am

    DSM

    SMTWTFS

  10. AA3832

    American Airlines

    05:26 am

    FSD

    1.7h

    07:07 am

    ORD

    SMTWTFS
    Search

  11. AA6048

    American Airlines

    03:10 pm

    ORD

    1.3h

    04:26 pm

    DSM

    SMTWTFS

  12. UA1464

    United Airlines

    08:05 am

    FSD

    1.8h

    09:54 am

    ORD

    SMTWTFS
    Search

  13. UA3569

    United Airlines

    04:05 pm

    ORD

    1.6h

    05:40 pm

    DSM

    SMTWTFS

  14. UA1611

    United Airlines

    09:15 am

    FSD

    1.9h

    10:08 am

    DEN

    SMTWTFS
    Search

  15. UA1925

    United Airlines

    05:50 pm

    DEN

    1.7h

    08:34 pm

    DSM

    SMTWTFS

  16. DL5261

    Delta Air Lines

    10:58 am

    FSD

    1.1h

    12:04 pm

    MSP

    SMTWTFS
    Search

  17. DL5063

    Delta Air Lines

    03:30 pm

    MSP

    1.2h

    04:40 pm

    DSM

    SMTWT-S

  18. DL5261

    Delta Air Lines

    10:58 am

    FSD

    1.1h

    12:04 pm

    MSP

    SMTWTFS
    Search

  19. DL4998

    Delta Air Lines

    09:00 am

    MSP

    1.2h

    10:11 am

    DSM

    SMTWTFS

  20. AA6023

    American Airlines

    12:23 pm

    FSD

    1.7h

    02:06 pm

    ORD

    SMTWTFS
    Search

  21. AA4665

    American Airlines

    08:55 pm

    ORD

    1.6h

    10:28 pm

    DSM

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Sioux Falls to Des Moines?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Sioux Falls (FSD) to Des Moines (DSM) the cheapest?

    Airlines adjust prices for flights from Sioux Falls to Des Moines based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Sioux Falls (FSD) to Des Moines (DSM) cost?

    According to Trip.com's data, the lowest price is around US$468.

  • How long does it take to fly from Sioux Falls (FSD) to Des Moines (DSM) and what is the distance?

    It takes around 55 minutes to fly from Sioux Falls (FSD) to Des Moines (DSM).

  • What are the most popular airlines that fly from Sioux Falls (FSD) to Des Moines (DSM)?

    Airlines with flights from Sioux Falls (FSD) to Des Moines (DSM): Sun Country Airlines.

How to find a cheap flight from Sioux Falls to Des Moines

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Sioux Falls to Des Moines. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Sioux Falls to Des Moines

Cheapest nonstop flight priceUS$251
Off-season for travelJanuary
Peak season for travelDecember
Flight distance340.04 km
Average flight time55 minutes
Popular airlineAmerican Airlines

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