App
Customer Support
PHP
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from San Diego to Knoxville Starting at PHP 8,919

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip
      • SAN06:25 am
        5h 58m
        1 stop
        TYS03:23 pm
        Thu, Mar 6|San Diego - Knoxville|Frontier Airlines
        PHP 8,919PHP 21,327
        57% OFF
        57% OFF
        PHP 21,327PHP 8,919

        Choose Frontier Airlines flights from San Diego to Knoxville. The one-way connecting flight with Frontier Airlines departs from San Diego International Airport on Thu, Mar 6, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 8,919 including taxes and charges.

      • SAN06:25 am
        6h 16m
        1 stop
        TYS03:41 pm
        Thu, Apr 17|San Diego - Knoxville|Frontier Airlines
        PHP 9,095PHP 21,327
        56% OFF
        56% OFF
        PHP 21,327PHP 9,095

        Choose Frontier Airlines flights from San Diego to Knoxville. The one-way connecting flight with Frontier Airlines departs from San Diego International Airport on Thu, Apr 17, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 9,095 including taxes and charges.

      • SAN08:00 am
        7h 7m
        1 stop
        TYS06:07 pm
        Tue, Mar 4|San Diego - Knoxville|United Airlines
        PHP 9,134PHP 21,327
        56% OFF
        56% OFF
        PHP 21,327PHP 9,134

        Choose United Airlines flights from San Diego to Knoxville. The one-way connecting flight with United Airlines departs from San Diego International Airport on Tue, Mar 4, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 9,134 including taxes and charges.

      • SAN12:19 pm
        24h 22m
        1 stop
        TYS03:41 pm
        Wed, Apr 2|San Diego - Knoxville|Frontier Airlines
        PHP 9,262
        PHP 9,262

        Choose Frontier Airlines flights from San Diego to Knoxville. The one-way connecting flight with Frontier Airlines departs from San Diego International Airport on Wed, Apr 2, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 9,262 including taxes and charges.

      • SAN02:40 pm
        6h 2m
        1 stop
        TYS11:42 pm
        Wed, Apr 2|San Diego - Knoxville|Delta Air Lines
        PHP 9,892
        PHP 9,892

        Choose Delta Air Lines flights from San Diego to Knoxville. The one-way connecting flight with Delta Air Lines departs from San Diego International Airport on Wed, Apr 2, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 9,892 including taxes and charges.

      • SAN09:45 pm
        9h 20m
        1 stop
        TYS10:05 am
        Wed, Apr 2|San Diego - Knoxville|United Airlines
        PHP 12,429
        PHP 12,429

        Choose United Airlines flights from San Diego to Knoxville. The one-way connecting flight with United Airlines departs from San Diego International Airport on Wed, Apr 2, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 12,429 including taxes and charges.

      • SAN10:40 pm
        7h 31m
        1 stop
        TYS09:11 am
        Sun, May 11|San Diego - Knoxville|Delta Air Lines
        PHP 15,788
        PHP 15,788

        Choose Delta Air Lines flights from San Diego to Knoxville. The one-way connecting flight with Delta Air Lines departs from San Diego International Airport on Sun, May 11, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 15,788 including taxes and charges.

      • SAN06:50 pm
        12h 10m
        1 stop
        TYS10:00 am
        Wed, Mar 26|San Diego - Knoxville|United Airlines
        PHP 15,852
        PHP 15,852

        Choose United Airlines flights from San Diego to Knoxville. The one-way connecting flight with United Airlines departs from San Diego International Airport on Wed, Mar 26, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 15,852 including taxes and charges.

      • SAN02:40 pm
        6h 2m
        1 stop
        TYS11:42 pm
        Mon, Mar 10|San Diego - Knoxville|Delta Air Lines
        PHP 15,899
        PHP 15,899

        Choose Delta Air Lines flights from San Diego to Knoxville. The one-way connecting flight with Delta Air Lines departs from San Diego International Airport on Mon, Mar 10, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 15,899 including taxes and charges.

      • SAN10:10 pm
        8h 53m
        1 stop
        TYS10:03 am
        Thu, May 8|San Diego - Knoxville|Delta Air Lines
        PHP 15,899
        PHP 15,899

        Choose Delta Air Lines flights from San Diego to Knoxville. The one-way connecting flight with Delta Air Lines departs from San Diego International Airport on Thu, May 8, arriving at Mcghee Tyson Airport. One-way Prices start from PHP 15,899 including taxes and charges.

      • SAN01:00 pm
        3h 5m
        Nonstop
        TYS02:00 pm
        Tue, Mar 4|San Diego - Knoxville|Frontier Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

San Diego to Knoxville Flight Time

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL894

    Delta Air Lines

    01:58 pm

    SAN

    4.4h

    09:21 pm

    ATL

    S--WT-S
    Search

  2. DL3072

    Delta Air Lines

    10:55 pm

    ATL

    0.9h

    11:51 pm

    TYS

    SMTWTFS

  3. AS6035

    Alaska Airlines

    07:15 am

    SAN

    3.2h

    12:29 pm

    DFW

    S-TWT-S
    Search

  4. AS4127

    Alaska Airlines

    02:25 pm

    DFW

    2.1h

    05:31 pm

    TYS

    SMTWTFS

  5. DL762

    Delta Air Lines

    08:00 am

    SAN

    4.2h

    03:14 pm

    ATL

    SMTWTFS
    Search

  6. DL5203

    Delta Air Lines

    06:55 pm

    ATL

    1.0h

    07:54 pm

    TYS

    SMTWT-S

  7. UA2472

    United Airlines

    08:00 am

    SAN

    3.1h

    01:06 pm

    IAH

    SMTWTFS
    Search

  8. UA4890

    United Airlines

    02:45 pm

    IAH

    2.4h

    06:11 pm

    TYS

    SMTWTFS

  9. UA2129

    United Airlines

    09:45 pm

    SAN

    5.0h

    05:44 am

    IAD

    SMTWTFS
    Search

  10. UA4257

    United Airlines

    08:45 am

    IAD

    1.7h

    10:27 am

    TYS

    SMTWTFS

  11. UA264

    United Airlines

    11:31 am

    SAN

    2.5h

    02:59 pm

    DEN

    SMTWT-S
    Search

  12. UA4798

    United Airlines

    05:26 pm

    DEN

    3.0h

    10:28 pm

    TYS

    SMTWTFS

  13. AA1946

    American Airlines

    12:54 pm

    SAN

    2.9h

    05:47 pm

    DFW

    SMTWTFS
    Search

  14. AA1081

    American Airlines

    08:50 pm

    DFW

    2.0h

    11:49 pm

    TYS

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from San Diego to Knoxville?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from San Diego (SAN) to Knoxville (TYS) the cheapest?

    Airlines adjust prices for flights from San Diego to Knoxville based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from San Diego (SAN) to Knoxville (TYS) cost?

    According to Trip.com's data, the lowest price is around PHP 26,661.

How to find a cheap flight from San Diego to Knoxville

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Diego to Knoxville. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | San Diego to Knoxville

Cheapest nonstop flight pricePHP 8,919
Off-season for travelJanuary
Peak season for travelNovember
Flight distance3,054.23 km
Popular airlineAmerican Airlines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.