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Cheap flight deals from Myrtle Beach to Santa Ana Starting at US$214

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip
      • MYR02:15 pm
        8h 28m
        1 stop
        SNA07:43 pm
        Thu, Feb 27|Myrtle Beach - Santa Ana|Delta Air Lines
        US$214US$1,080
        80% OFF
        80% OFF
        US$1,080US$214

        Choose Delta Air Lines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with Delta Air Lines departs from Myrtle Beach International Airport on Thu, Feb 27, arriving at John Wayne Airport. One-way Prices start from US$214 including taxes and charges.

      • MYR11:54 am
        9h 35m
        1 stop
        SNA06:29 pm
        Tue, Apr 1|Myrtle Beach - Santa Ana|United Airlines
        US$231US$1,080
        79% OFF
        79% OFF
        US$1,080US$231

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Tue, Apr 1, arriving at John Wayne Airport. One-way Prices start from US$231 including taxes and charges.

      • MYR02:08 pm
        8h 39m
        1 stop
        SNA07:47 pm
        Tue, Apr 1|Myrtle Beach - Santa Ana|Delta Air Lines
        US$234US$1,080
        78% OFF
        78% OFF
        US$1,080US$234

        Choose Delta Air Lines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with Delta Air Lines departs from Myrtle Beach International Airport on Tue, Apr 1, arriving at John Wayne Airport. One-way Prices start from US$234 including taxes and charges.

      • MYR02:53 pm
        9h 52m
        1 stop
        SNA09:45 pm
        Tue, Mar 4|Myrtle Beach - Santa Ana|United Airlines
        US$317
        US$317

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Tue, Mar 4, arriving at John Wayne Airport. One-way Prices start from US$317 including taxes and charges.

      • MYR02:53 pm
        9h 52m
        1 stop
        SNA09:45 pm
        Thu, Feb 27|Myrtle Beach - Santa Ana|United Airlines
        US$365
        US$365

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Thu, Feb 27, arriving at John Wayne Airport. One-way Prices start from US$365 including taxes and charges.

      • MYR02:35 pm
        9h 51m
        1 stop
        SNA09:26 pm
        Thu, Mar 6|Myrtle Beach - Santa Ana|United Airlines
        US$451
        US$451

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Thu, Mar 6, arriving at John Wayne Airport. One-way Prices start from US$451 including taxes and charges.

      • MYR06:00 am
        9h 3m
        1 stop
        SNA12:03 pm
        Thu, Mar 6|Myrtle Beach - Santa Ana|Delta Air Lines
        US$466
        US$466

        Choose Delta Air Lines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with Delta Air Lines departs from Myrtle Beach International Airport on Thu, Mar 6, arriving at John Wayne Airport. One-way Prices start from US$466 including taxes and charges.

      • MYR02:32 pm
        9h 54m
        1 stop
        SNA09:26 pm
        Fri, Mar 7|Myrtle Beach - Santa Ana|United Airlines
        US$522
        US$522

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Fri, Mar 7, arriving at John Wayne Airport. One-way Prices start from US$522 including taxes and charges.

      • MYR02:32 pm
        9h 54m
        1 stop
        SNA09:26 pm
        Sun, Mar 16|Myrtle Beach - Santa Ana|United Airlines
        US$808
        US$808

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Sun, Mar 16, arriving at John Wayne Airport. One-way Prices start from US$808 including taxes and charges.

      • MYR11:54 am
        9h 35m
        1 stop
        SNA06:29 pm
        Sat, Apr 12|Myrtle Beach - Santa Ana|United Airlines
        US$821
        US$821

        Choose United Airlines flights from Myrtle Beach to Santa Ana. The one-way connecting flight with United Airlines departs from Myrtle Beach International Airport on Sat, Apr 12, arriving at John Wayne Airport. One-way Prices start from US$821 including taxes and charges.

      • MYR01:00 pm
        3h 5m
        Nonstop
        SNA02:00 pm
        Wed, Feb 26|Myrtle Beach - Santa Ana|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Myrtle Beach to Santa Ana Flight Time

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3182

    Delta Air Lines

    01:05 pm

    MYR

    1.4h

    02:27 pm

    ATL

    SMTWT-S
    Search

  2. DL543

    Delta Air Lines

    05:45 pm

    ATL

    5.0h

    07:43 pm

    SNA

    SMTWTFS

  3. UA3638

    United Airlines

    01:37 pm

    MYR

    2.0h

    03:40 pm

    EWR

    SMTWTFS
    Search

  4. UA1293

    United Airlines

    06:19 pm

    EWR

    6.4h

    09:45 pm

    SNA

    SMTWTFS

  5. AA5331

    American Airlines

    03:00 pm

    MYR

    1.1h

    04:07 pm

    CLT

    SMTWTFS
    Search

  6. AA2503

    American Airlines

    06:30 pm

    CLT

    5.4h

    08:54 pm

    SNA

    SMTWTFS

  7. DL3170

    Delta Air Lines

    03:40 pm

    MYR

    1.4h

    05:05 pm

    ATL

    S--WTFS
    Search

  8. DL329

    Delta Air Lines

    10:00 am

    ATL

    5.0h

    12:03 pm

    SNA

    SMTWTFS

  9. DL3170

    Delta Air Lines

    03:40 pm

    MYR

    1.4h

    05:05 pm

    ATL

    S--WTFS
    Search

  10. DL493

    Delta Air Lines

    08:55 pm

    ATL

    3.4h

    10:19 pm

    DEN

    SMTWTFS

  11. F94371

    Frontier Airlines

    09:59 am

    DEN

    2.5h

    11:28 am

    SNA

    SMTWTFS

  12. DL3162

    Delta Air Lines

    06:00 am

    MYR

    1.4h

    07:24 am

    ATL

    SMTWTFS
    Search

  13. DL774

    Delta Air Lines

    09:40 am

    ATL

    5.6h

    12:16 pm

    SEA

    SMTWTFS

  14. DL2318

    Delta Air Lines

    03:30 pm

    SEA

    2.8h

    06:20 pm

    SNA

    SMTWTFS

  15. DL3162

    Delta Air Lines

    06:00 am

    MYR

    1.4h

    07:24 am

    ATL

    SMTWTFS
    Search

  16. DL329

    Delta Air Lines

    10:00 am

    ATL

    5.0h

    12:03 pm

    SNA

    SMTWTFS

  17. AA3246

    American Airlines

    07:00 am

    MYR

    1.1h

    08:08 am

    CLT

    SMTWTFS
    Search

  18. AA3150

    American Airlines

    09:30 am

    CLT

    5.0h

    11:27 am

    PHX

    SMTWTFS

  19. AA2463

    American Airlines

    01:59 pm

    PHX

    1.3h

    03:16 pm

    SNA

    SMTWTFS

  20. NK1993

    Spirit Airlines

    08:58 am

    MYR

    2.1h

    11:07 am

    BOS

    SMTWTFS
    Search

  21. AA1545

    American Airlines

    02:08 pm

    BOS

    4.8h

    05:58 pm

    DFW

    SMTWTFS

  22. AA806

    American Airlines

    06:50 pm

    DFW

    3.5h

    08:18 pm

    SNA

    SMTWTFS

  23. DL3047

    Delta Air Lines

    10:55 am

    MYR

    1.4h

    12:16 pm

    ATL

    SMTWTFS
    Search

  24. DL543

    Delta Air Lines

    05:45 pm

    ATL

    5.0h

    07:43 pm

    SNA

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Myrtle Beach to Santa Ana?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Myrtle Beach (MYR) to Santa Ana (SNA) the cheapest?

    Airlines adjust prices for flights from Myrtle Beach to Santa Ana based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Myrtle Beach (MYR) to Santa Ana (SNA) cost?

    According to Trip.com's data, the lowest price is around US$456.

  • What is the transportation method from the main airport to downtown in Santa Ana?

    • The distance from John Wayne Airport to downtown is about 7 km. It takes about 20 minutes by taxi.

How to find a cheap flight from Myrtle Beach to Santa Ana

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Myrtle Beach to Santa Ana. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Myrtle Beach to Santa Ana

Cheapest nonstop flight priceUS$214
Off-season for travelJanuary
Peak season for travelMarch
Flight distance3,577.34 km
Popular airlineDelta Air Lines

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