App
Customer Support
EUR
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from Medellin to Grand Cayman Starting at €308

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip
      • MDE01:10 pm
        8h 10m
        1 stop
        GCM09:20 pm
        Fri, Mar 21|Medellin - Grand Cayman|avianca
        €308€644
        52% OFF
        52% OFF
        €644€308

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Fri, Mar 21, arriving at Owen Roberts International Airport. One-way Prices start from €308 including taxes and charges.

      • MDE11:50 pm
        16h 20m
        1 stop
        GCM04:10 pm
        Mon, Mar 31|Medellin - Grand Cayman|avianca
        €334€644
        48% OFF
        48% OFF
        €644€334

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Mon, Mar 31, arriving at Owen Roberts International Airport. One-way Prices start from €334 including taxes and charges.

      • MDE01:10 pm
        27h
        1 stop
        GCM04:10 pm
        Mon, Mar 3|Medellin - Grand Cayman|avianca
        €339€644
        47% OFF
        47% OFF
        €644€339

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Mon, Mar 3, arriving at Owen Roberts International Airport. One-way Prices start from €339 including taxes and charges.

      • MDE11:50 pm
        16h 20m
        1 stop
        GCM04:10 pm
        Sun, Mar 30|Medellin - Grand Cayman|avianca
        €383
        €383

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Sun, Mar 30, arriving at Owen Roberts International Airport. One-way Prices start from €383 including taxes and charges.

      • MDE11:50 pm
        21h 30m
        1 stop
        GCM09:20 pm
        Thu, Apr 3|Medellin - Grand Cayman|avianca
        €401
        €401

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Thu, Apr 3, arriving at Owen Roberts International Airport. One-way Prices start from €401 including taxes and charges.

      • MDE11:50 pm
        11h 50m
        1 stop
        GCM11:40 am
        Thu, May 1|Medellin - Grand Cayman|avianca
        €403
        €403

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Thu, May 1, arriving at Owen Roberts International Airport. One-way Prices start from €403 including taxes and charges.

      • MDE01:10 pm
        27h
        1 stop
        GCM04:10 pm
        Sun, Mar 9|Medellin - Grand Cayman|avianca
        €428
        €428

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Sun, Mar 9, arriving at Owen Roberts International Airport. One-way Prices start from €428 including taxes and charges.

      • MDE01:10 pm
        22h 30m
        1 stop
        GCM11:40 am
        Thu, Mar 20|Medellin - Grand Cayman|avianca
        €456
        €456

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Thu, Mar 20, arriving at Owen Roberts International Airport. One-way Prices start from €456 including taxes and charges.

      • MDE01:10 pm
        8h 10m
        1 stop
        GCM09:20 pm
        Fri, Mar 28|Medellin - Grand Cayman|avianca
        €473
        €473

        Choose avianca flights from Medellin to Grand Cayman. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Fri, Mar 28, arriving at Owen Roberts International Airport. One-way Prices start from €473 including taxes and charges.

      • MDE06:00 am
        12h 40m
        1 stop
        GCM06:40 pm
        Sun, Mar 9|Medellin - Grand Cayman|American Airlines
        €489
        €489

        Choose American Airlines flights from Medellin to Grand Cayman. The one-way connecting flight with American Airlines departs from Jose Marie Cordova Airport on Sun, Mar 9, arriving at Owen Roberts International Airport. One-way Prices start from €489 including taxes and charges.

      • MDE01:00 pm
        3h 5m
        Nonstop
        GCM02:00 pm
        Wed, Feb 26|Medellin - Grand Cayman|avianca
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Medellin to Grand Cayman Flight Time

Flight info.
Departure
Arrival
Weekly Schedule

  1. LA4039

    LATAM Airlines

    02:48 am

    MDE

    0.9h

    03:45 am

    BOG

    S-T--FS
    Search

  2. LA4400

    LATAM Airlines

    07:00 am

    BOG

    3.9h

    11:56 am

    MIA

    SMTWTFS

  3. KX105

    Cayman Airways

    03:30 pm

    MIA

    1.7h

    04:10 pm

    GCM

    SMTW-F-

  4. CM151

    Copa Airlines

    05:06 am

    MDE

    1.5h

    06:34 am

    PTY

    SMTWTFS
    Search

  5. CM226

    Copa Airlines

    08:01 am

    PTY

    3.3h

    12:16 pm

    MIA

    SMTWTFS

  6. KX105

    Cayman Airways

    03:30 pm

    MIA

    1.7h

    04:10 pm

    GCM

    SMTW-F-

  7. AA924

    American Airlines

    06:00 am

    MDE

    3.7h

    10:40 am

    MIA

    SMTWTFS
    Search

  8. KX109

    Cayman Airways

    06:00 pm

    MIA

    1.7h

    06:40 pm

    GCM

    ------S

  9. CM209

    Copa Airlines

    06:39 am

    MDE

    1.5h

    08:07 am

    PTY

    SMTWTFS
    Search

  10. CM393

    Copa Airlines

    09:04 am

    PTY

    3.4h

    01:26 pm

    TPA

    SMTWTFS

  11. KX203

    Cayman Airways

    04:30 pm

    TPA

    1.8h

    05:20 pm

    GCM

    S--W---

  12. CM209

    Copa Airlines

    06:39 am

    MDE

    1.5h

    08:07 am

    PTY

    SMTWTFS
    Search

  13. CM334

    Copa Airlines

    10:25 am

    PTY

    3.3h

    02:40 pm

    MIA

    SMTW-FS

  14. KX109

    Cayman Airways

    06:00 pm

    MIA

    1.7h

    06:40 pm

    GCM

    ------S

  15. AV138

    avianca

    08:20 am

    MDE

    3.6h

    11:55 am

    MIA

    SMTWTFS
    Search

  16. KX105

    Cayman Airways

    03:30 pm

    MIA

    1.7h

    04:10 pm

    GCM

    SMTW-F-

  17. CM398

    Copa Airlines

    09:14 am

    MDE

    1.5h

    10:42 am

    PTY

    SMTWTFS
    Search

  18. CM485

    Copa Airlines

    12:48 pm

    PTY

    3.3h

    05:03 pm

    MIA

    SMTWTFS

  19. KX107

    Cayman Airways

    08:40 pm

    MIA

    1.7h

    09:20 pm

    GCM

    ---WT--

  20. LA4017

    LATAM Airlines

    09:34 am

    MDE

    0.9h

    10:30 am

    BOG

    SMTWTFS
    Search

  21. LA4402

    LATAM Airlines

    11:00 am

    BOG

    4.0h

    02:57 pm

    MIA

    SMTWTFS

  22. KX107

    Cayman Airways

    08:40 pm

    MIA

    1.7h

    09:20 pm

    GCM

    ---WT--

  23. LA4025

    LATAM Airlines

    11:53 pm

    MDE

    0.9h

    12:50 am

    BOG

    -MTWT-S
    Search

  24. LA4400

    LATAM Airlines

    07:00 am

    BOG

    3.9h

    11:56 am

    MIA

    SMTWTFS

  25. KX105

    Cayman Airways

    03:30 pm

    MIA

    1.7h

    04:10 pm

    GCM

    SMTW-F-

  26. AV030

    avianca

    12:35 pm

    MDE

    3.7h

    05:15 pm

    MIA

    SMTWTFS
    Search

  27. KX107

    Cayman Airways

    08:40 pm

    MIA

    1.7h

    09:20 pm

    GCM

    ---WT--
Find more flights and airlines

When is the cheapest time to fly from Medellin to Grand Cayman?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Medellin (MDE) to Grand Cayman (GCM) the cheapest?

    Airlines adjust prices for flights from Medellin to Grand Cayman based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Medellin (MDE) to Grand Cayman (GCM) cost?

    According to Trip.com's data, the lowest price is around €656.

  • What is the transportation method from the main airport to downtown in Grand Cayman?

    • The distance from Owen Roberts International Airport to downtown is about 11 km. It takes about 30 minutes by taxi.

How to find a cheap flight from Medellin to Grand Cayman

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to Grand Cayman. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Medellin to Grand Cayman

Cheapest nonstop flight price€307
Off-season for travelMarch
Peak season for travelNovember
Flight distance1,580.79 km
Popular airlineavianca

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.