Cheap Flights from Des Moines to Grand Cayman from €249

Frequently Asked Questions

• What are the cheapest flights from Des Moines to Grand Cayman (DSM-GCM)?

  Based on Trip.com data, Frontier Airlines offers one-way fares as low as €249 on Cheapest nonstop routes (e.g. DSM to GCM on Fri, Jan 16), while Delta Air Lines offers Cheapest nonstop round-trips from €420 departing on Tue, Jan 6 and returning on Tue, Jan 13.

• When is the best time to book flights from Des Moines to Grand Cayman?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Des Moines to Grand Cayman is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How can I find the best deals on flights from Des Moines to Grand Cayman?

  To find best deals on flights from Des Moines to Grand Cayman, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Jan 16, with one-way flights priced at just €249.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Frontier Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Grand Cayman travel is around September.
  · Get exclusive promo codes for Trip.com app users.

• When are flight tickets from Des Moines (DSM) to Grand Cayman (GCM) the cheapest?

  The cheapest months to fly from Des Moines to Grand Cayman is November, when demand for travel is lower.

• Which upcoming date is cheapest to fly from Des Moines to Grand Cayman on?

  After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Des Moines to Grand Cayman on December 10, 2025 with Delta Air Lines, with prices starting at €519.

• Is there any time difference between Des Moines and Grand Cayman?

  The time difference between Grand Cayman and Des Moines is 1h.

• How do I change or cancel my ticket from Des Moines to Grand Cayman?

  Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.