App
Customer Support
PHP
Find Bookings
Trip.com
>
Flights
>
Flights to Chile
>
Flights to Antofagasta
>
Flights from Des Moines to Antofagasta
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from Des Moines to Antofagasta Starting at PHP 36,145

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • One way
  • Round-trip
      • DSM11:27 am
        39h 3m
        2 stops
        ANF04:30 am
        Tue, Mar 25|Des Moines - Antofagasta|Delta Air Lines
        PHP 36,145PHP 91,160
        60% OFF
        60% OFF
        PHP 91,160PHP 36,145

        Choose Delta Air Lines flights from Des Moines to Antofagasta. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Tue, Mar 25, arriving at ANF Airport. One-way Prices start from PHP 36,145 including taxes and charges.

      • DSM03:45 pm
        33h 45m
        2 stops
        ANF04:30 am
        Thu, Feb 20|Des Moines - Antofagasta|Southwest Airlines
        PHP 69,282PHP 91,160
        24% OFF
        24% OFF
        PHP 91,160PHP 69,282

        Choose Southwest Airlines flights from Des Moines to Antofagasta. The one-way connecting flight with Southwest Airlines departs from Des Moines International Airport on Thu, Feb 20, arriving at ANF Airport. One-way Prices start from PHP 69,282 including taxes and charges.

      • DSM01:00 pm
        3h 5m
        Nonstop
        ANF02:00 pm
        Wed, Feb 26|Des Moines - Antofagasta|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Des Moines to Antofagasta Flight Time

Flight info.
Departure
Arrival
Weekly Schedule

  1. WN332

    Southwest Airlines

    03:45 pm

    DSM

    5.3h

    07:00 pm

    ONT

    SM-W---
    Search

  2. LA2479

    LATAM Airlines

    11:20 am

    LAX

    8.6h

    10:55 pm

    LIM

    SMTWTFS

  3. LA2373

    LATAM Airlines

    11:40 pm

    LIM

    2.4h

    03:05 am

    ANF

    -M-W-F-

  4. DL447

    Delta Air Lines

    05:33 am

    DSM

    2.4h

    08:54 am

    ATL

    SMTWTFS
    Search

  5. DL147

    Delta Air Lines

    09:55 pm

    ATL

    9.1h

    07:00 am

    SCL

    SMTWTFS

  6. LA362

    LATAM Airlines

    09:11 pm

    SCL

    2.0h

    11:14 pm

    ANF

    -MT-T-S

  7. LA6830

    LATAM Airlines

    05:45 am

    DSM

    2.3h

    09:00 am

    ATL

    SMTWTFS
    Search

  8. LA6357

    LATAM Airlines

    09:55 pm

    ATL

    9.1h

    07:00 am

    SCL

    SMTWTFS

  9. JA054

    JetSMART Airlines

    03:19 pm

    SCL

    2.1h

    05:23 pm

    ANF

    S-T-T--

  10. LA6830

    LATAM Airlines

    05:45 am

    DSM

    2.3h

    09:00 am

    ATL

    SMTWTFS
    Search

  11. LA6357

    LATAM Airlines

    09:55 pm

    ATL

    9.1h

    07:00 am

    SCL

    SMTWTFS

  12. LA362

    LATAM Airlines

    09:11 pm

    SCL

    2.0h

    11:14 pm

    ANF

    -MT-T-S

  13. AA3522

    American Airlines

    06:59 am

    DSM

    3.4h

    11:20 am

    MIA

    SMTWTFS
    Search

  14. AA957

    American Airlines

    10:55 pm

    MIA

    8.2h

    07:05 am

    SCL

    SMTWTFS

  15. AA7796

    American Airlines

    05:09 am

    SCL

    2.1h

    07:13 am

    ANF

    --T----

  16. UA1982

    United Airlines

    08:00 am

    DSM

    2.6h

    10:36 am

    IAH

    SMTWTFS
    Search

  17. UA847

    United Airlines

    08:25 pm

    IAH

    9.4h

    08:50 am

    SCL

    SMTWTFS

  18. H2270

    Sky Airline

    05:13 am

    SCL

    2.0h

    07:13 am

    ANF

    S-T-T-S

  19. UA1982

    United Airlines

    08:00 am

    DSM

    2.6h

    10:36 am

    IAH

    SMTWTFS
    Search

  20. UA847

    United Airlines

    08:25 pm

    IAH

    9.4h

    08:50 am

    SCL

    SMTWTFS

  21. LA130

    LATAM Airlines

    09:02 am

    SCL

    2.0h

    11:04 am

    ANF

    SMTWTFS

  22. LA6849

    LATAM Airlines

    11:04 am

    DSM

    2.2h

    02:16 pm

    ATL

    SMTWTFS
    Search

  23. LA6357

    LATAM Airlines

    09:55 pm

    ATL

    9.1h

    07:00 am

    SCL

    SMTWTFS

  24. H2272

    Sky Airline

    04:29 am

    SCL

    2.0h

    06:30 am

    ANF

    SMTW--S

  25. DL1704

    Delta Air Lines

    11:04 am

    DSM

    2.1h

    02:13 pm

    ATL

    SMTWTFS
    Search

  26. LA2483

    LATAM Airlines

    11:20 pm

    ATL

    6.7h

    05:00 am

    LIM

    SMTWTFS

  27. LA2373

    LATAM Airlines

    11:40 pm

    LIM

    2.4h

    03:05 am

    ANF

    -M-W-F-
Find more flights and airlines

When is the cheapest time to fly from Des Moines to Antofagasta?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to Antofagasta (ANF) the cheapest?

    Airlines adjust prices for flights from Des Moines to Antofagasta based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to Antofagasta (ANF) cost?

    According to Trip.com's data, the lowest price is around PHP 82,968.

  • What is the transportation method from the main airport to downtown in Antofagasta?

    • The distance from ANF Airport to downtown is about 22 km. It takes about 40 minutes by taxi.

How to find a cheap flight from Des Moines to Antofagasta

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Des Moines to Antofagasta. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Des Moines to Antofagasta

Off-season for travelMarch
Peak season for travelFebruary
Flight distance7,610.96 km
Popular airlineAmerican Airlines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.